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Section VIII – Infectious DiseasesSection Editors:Christopher Hoffmann, MD, MPH   Nicola Zetola, MDChapter 53 – Fever of Unknown OriginScott Kim, MD   Rachel Damico, MD, PhD   Paul Auwaerter, MDFAST FACTS   ▪    The contemporary understanding of fever of unknown origin (FUO) is derived from Petersdorf and Beeson's 1961 characterization of FUO. A stringent definition of FUO is composed of the following criteria[1]: temperature higher than 38.3° C measured on several occasions, 3-week duration (to exclude self-limiting fevers), negative blood cultures, no apparent explanation, and three outpatient visits or three hospital days.   ▪    Infections, malignancies, and noninfectious inflammatory diseases account for the majority of cases of FUO.   ▪    In patients older than 65 years, temporal arteritis should be considered early in any evaluation.   ▪    Patients with FUO who remain undiagnosed after exhaustive study usually have a favorable prognosis. In one study, in a cohort of 61 patients with FUO discharged without diagnosis, the 5-year mortality rate was only 3.2%.[2]…

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On the dark road ahead,I can't see a single step aheadI can't see anythingI can't feel anything- Colors Yoori felt restless. She had been sitting alone for at least 30 minutes. There was no familiar face so far. She only knows Jane and she was there because of her. Jane was supposed to fly Paris to pursue her study there as an exchange student tomorrow, so Yoori was invited to celebrate it. She felt kinda awkward amidst of the dancing crowd. She was not really a sociable person.Few minutes later, she finally saw a familiar face. Brian Kang. He was walking toward her who was sitting on the coach located at the corner of the club. Yoori nervously put down her drink. Yoori's heart skipped a beat when his manly scent hit her smell sense. Jane was so lucky to have Brian as her boyfriend. He's handsome, caring and romantic. But Brian is luckier to be Jane's boyfriend. She is the most attractive person in their campus. She excelled in studies and her modelling career. She is friendly, brave and beautiful. A social butterfly.So why would that Jane befriend of someone like Yoori? Yoori was not sure. But for sure, they started to talk to each other since Jane saved her from beaten by her dad in front of their campus gate."Hi," he said. Yoori acknowledged his present with a nod. They never talked to each other before eventhough they heard a lot about each other from Jane. "Do you want to stay here longer?""Huh? Where is Jane?" Yoori asked without looking at him. It had been a while since she last talked to a guy. Except her lecturers. And the loan shark who comes to her house every month. She had to agree it was rather awkward."She--""HELLO, LADIES AND GENTLEMEN!""UGH SHUT UP, JAE!""YOU SHUT UP. I'M TALKING TO MY HOMIE HERE. NOT TO YOU."Yoori knew this couple. They were like the noisiest couple ever. They fought a lot but everyone knows after each fight Mery will run into Jae's arm again. They could not be separated. At least, not for too long.…